BDBM12857 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-(2-{[(3S)-3-hydroxypyrrolidin-1-yl]methyl}phenyl)phenyl]-3-methyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one::Pyrazolo[4,3-d]pyrimidinone 19c
SMILES Cc1nn(-c2ccc3onc(N)c3c2)c2c1ncn(-c1ccc(cc1)-c1ccccc1CN1CC[C@H](O)C1)c2=O
InChI Key InChIKey=MZTLUQWQCIFDEZ-QHCPKHFHSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 12857
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 0.5nM ΔG°: -12.6kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair