BDBM12919 4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole::4-sulfamoyl-N-({1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide::CHEMBL385152::Glycoconjugate Benzene Sulfonamide 2aa

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1cn(nn1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=DIVMUZMLCIWZTE-XYFZXANASA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 12919   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  8.20nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant CA14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  11.4nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  11.4nMAssay Description:Inhibition of human recombinant CA12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  442nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  442nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12919(4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta...)
Affinity DataKi:  2.00E+3nM ΔG°:  -7.77kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed