BDBM13032 3-(fluoromethyl)-N-(2-methoxyethyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide::7-sulfonamide-THIQ 22::CHEMBL184931
SMILES COCCNS(=O)(=O)c1ccc2CC(CF)NCc2c1
InChI Key InChIKey=LHCCAAULWCHZRM-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 13032
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataKi: 5.10E+3nMAssay Description:Inhibition of [3H]-methyl-AdoMet binding to human phenylethnolamine N-methyltransferase expressed in E. coli BL21More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataKi: 5.10E+3nM ΔG°: -7.51kcal/molepH: 8.0 T: 2°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair