BDBM130404 US8822505, 4

SMILES CC(C)(C)OC(=O)N1CC(C1)(C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccc(OCC(F)(F)F)cc1Cl)c1ccc(Cl)cn1

InChI Key InChIKey=JCEQLYSTWCEKGP-IRLDBZIGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130404   

TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130404(US8822505, 4)
Affinity DataIC50:  2.75nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130404(US8822505, 4)
Affinity DataIC50:  1.24E+3nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent