BDBM13144 (2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylbutanoyl]-N-(2-ethylbutyl)pyrrolidine-2-carboxamide::Smac peptido-mimetic 6b

SMILES CCC(CC)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C

InChI Key InChIKey=XEUNZZQOODTMLJ-BPUTZDHNSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13144   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13144((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...)
Affinity DataKi:  2.45E+4nM ΔG°:  -6.22kcal/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed