BDBM13262 BMS-354825 2-Heteroarylamino-thiazole Analog 12g::N-(2,6-dimethylphenyl)-2-(pyridazin-3-ylamino)-1,3-thiazole-5-carboxamide

SMILES Cc1cccc(C)c1NC(=O)c1cnc(Nc2cccnn2)s1

InChI Key InChIKey=QUDMBHOAMAEYBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13262   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM13262(BMS-354825 2-Heteroarylamino-thiazole Analog 12g |...)
Affinity DataIC50:  0.300nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed