BDBM13280 3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide::CHEMBL327600::Sulfonamidopyrrolidinone 3a
SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O
InChI Key InChIKey=LDJWHJQMWPYZLV-NRFANRHFSA-N
Data 13 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 13280
Affinity DataKi: 47nM ΔG°: -9.89kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complexMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:In vitro evaluation of inhibitory activity against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 853nM ΔG°: -8.19kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Compound was evaluated for the inhibition of activated protein C (aPC)More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:In vitro evaluation of inhibitory activity against Coagulation factor II in prothrombinase complexMore data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:Compound was evaluated for the inhibition of plasminMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair