BDBM13407 3-(3-chlorophenyl)-4-{[(1-methyl-1H-imidazol-5-yl)[4-(trifluoromethyl)phenyl]methoxy]methyl}benzonitrile::A313326 Analogue 51

SMILES Cn1cncc1C(OCc1ccc(cc1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XJFZJWINCCUFCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13407   

TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Globe Pharmaceutical R and Abbott Laboratories

LigandPNGBDBM13407(3-(3-chlorophenyl)-4-{[(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50:  1.10nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM13407(3-(3-chlorophenyl)-4-{[(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bos taurus (bovine))
Globe Pharmaceutical R and Abbott Laboratories

LigandPNGBDBM13407(3-(3-chlorophenyl)-4-{[(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50:  2.10E+3nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed