BDBM13414 A313326 Analogue 60c::N-(5-cyano-2-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy]methyl}phenyl)naphthalene-1-sulfonamide
SMILES Cn1cncc1C(OCc1ccc(cc1NS(=O)(=O)c1cccc2ccccc12)C#N)c1ccc(cc1)C#N
InChI Key InChIKey=AKKQWZHJOANNGA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 13414
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Globe Pharmaceutical R and Abbott Laboratories
Globe Pharmaceutical R and Abbott Laboratories
Affinity DataIC50: 2.60nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University Of Baroda
Curated by ChEMBL
The M.S. University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Bos taurus (bovine))
Globe Pharmaceutical R and Abbott Laboratories
Globe Pharmaceutical R and Abbott Laboratories
Affinity DataIC50: 100nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair