BDBM135234 US8846657, 3.127

SMILES C[C@H]1CCC(Cn2c(nc3cc(nc(-c4cncc(Cl)c4)c23)-c2noc(=O)[nH]2)N2CCO[C@@H]3CNCC[C@@H]23)CC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135234   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM135234(US8846657, 3.127)
Affinity DataIC50:  512nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In DepthDetails US Patent