BDBM13943 APC-1847::{amino[2-(2-methoxyphenyl)-1H-1,3-benzodiazol-5-yl]methylidene}azanium

SMILES COc1ccccc1-c1nc2ccc(cc2[nH]1)C(N)=[NH2+]

InChI Key InChIKey=FSIIIUKPMNRIFF-UHFFFAOYSA-O

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13943   

TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  6.70E+3nM ΔG°:  -6.98kcal/molepH: 8.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  8.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  1.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  1.70E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed