BDBM139687 US8894989, 74::US8894989, 75

SMILES O=c1[nH]nc2[nH]c(CNS(=O)(=O)c3ccccc3)nc3cccc1c23

InChI Key InChIKey=ORFYJYLOCQRHGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139687   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Eisai

US Patent
LigandPNGBDBM139687(US8894989, 74 | US8894989, 75)
Affinity DataIC50:  30nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Eisai

US Patent
LigandPNGBDBM139687(US8894989, 74 | US8894989, 75)
Affinity DataIC50:  23nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In DepthDetails US Patent