BDBM140239 US8906911, 48

SMILES FC(F)(F)c1ccc(C#N)c(c1)N1C[C@@H]2C[C@H]1CN2C(=O)[C@@]12CCC[C@@H]1C[C@H](C2)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=NPHOVOIBSSEVRR-XDNGOLROSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140239   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140239(US8906911, 48)
Affinity DataKi:  8nM ΔG°:  -10.3kcal/mole IC50:  51.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent