BDBM141377 US8916600, 11::US9738632, Example 11

SMILES CC[C@@H](O)CNC(=O)c1cccc(c1)-n1ncc2cc(O[C@@H]([C@H](C)NC(=O)C(C)(F)F)c3ccc4COCOc4c3)ccc12

InChI Key InChIKey=DFLABOCFUUEYAR-CIKSPIGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141377   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141377(US8916600, 11 | US9738632, Example 11)
Affinity DataIC50:  2.15nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141377(US8916600, 11 | US9738632, Example 11)
Affinity DataIC50:  2.15nMpH: 7.4 T: 2°CAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 uM. ...More data for this Ligand-Target Pair
In DepthDetails US Patent