BDBM14257 4-bromo-3-(carboxymethoxy)-5-[4-(furan-2-amido)phenyl]thiophene-2-carboxylic acid::Monocyclic thiophene analog 26

SMILES OC(=O)COc1c(Br)c(sc1C(O)=O)-c1ccc(NC(=O)c2ccco2)cc1

InChI Key InChIKey=RHRKRRTZVKHMGD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14257   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14257(4-bromo-3-(carboxymethoxy)-5-[4-(furan-2-amido)phe...)
Affinity DataKi:  620nM ΔG°:  -8.46kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed