BDBM14525 N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(methylamino)-2-oxo-6-phenyl-1,2-dihydropyrazin-1-yl]acetamide::Pyrazinone Analog 28a

SMILES CNc1nc(Cl)c(-c2ccccc2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O

InChI Key InChIKey=GHNPQZVQEKZFKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14525   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14525(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(m...)
Affinity DataIC50:  700nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14525(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(m...)
Affinity DataIC50:  2.04E+4nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed