BDBM14553 N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(4-hydroxybutyl)amino]-2-oxo-6-phenyl-1,2-dihydropyrazin-1-yl}acetamide::Pyrazinone Analog 28u

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCCCO)c2=O)-c2ccccc2)cc1

InChI Key InChIKey=OFFAMKJIIYJPIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14553   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14553(N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(...)
Affinity DataIC50:  600nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14553(N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(...)
Affinity DataIC50:  1.00E+4nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed