BDBM14587 3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}methyl)-3-chloro-6-oxo-5-(propan-2-ylamino)-1,6-dihydropyrazin-2-yl]benzoic acid::Pyrazinone Analog 32g

SMILES CC(C)Nc1nc(Cl)c(-c2cccc(c2)C(O)=O)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O

InChI Key InChIKey=DHQDQOMFUWGNEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14587   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14587(3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}me...)
Affinity DataIC50:  360nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14587(3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}me...)
Affinity DataIC50:  2.80E+3nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed