BDBM14588 N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-[3-(methylamino)phenyl]-2-oxo-3-[(2-phenylethyl)amino]-1,2-dihydropyrazin-1-yl}acetamide::Pyrazinone Analog 33a

SMILES CNc1cccc(c1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=ABAZYTXCHHQMTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14588   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14588(N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-[3...)
Affinity DataIC50:  600nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14588(N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-[3...)
Affinity DataIC50:  580nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed