BDBM146435 US8957068, 564
SMILES CC(C)COc1ccc(cc1)[C@H](C)Nc1ncc(F)c(n1)N1[C@H](COC1=O)C(C)C
InChI Key InChIKey=VNRQSKACLLUOAJ-HNAYVOBHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 146435
Affinity DataIC50: 50.1nMpH: 7.5 T: 25°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...More data for this Ligand-Target Pair