BDBM14754 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline::1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline::6,7-dimethoxy-1-veratryl-isoquinoline;hydrochloride::CHEMBL19224::Papaverine
SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
InChI Key InChIKey=XQYZDYMELSJDRZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 14754
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Competitive inhibition of rat recombinant PDE10A by scintillation proximity assay in presence of cAMPMore data for this Ligand-Target Pair