BDBM14782 5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ethyl ester::Pyrazole carboxylic ester 5::ethyl 3-(trifluoromethyl)-1H-pyrazole-4-carboxylate

SMILES CCOC(=O)c1cn[nH]c1C(F)(F)F

InChI Key InChIKey=VYXIHSAEOXPAEY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14782   

LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed