BDBM149461 US8975252, 4
SMILES COCCCOc1cc(CN(C2CC2)C(=O)[C@H]2CNCCO2)cc2ccccc12
InChI Key InChIKey=PXKWFPHRFQPVMA-JOCHJYFZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 149461
Affinity DataIC50: 30.2nMT: 2°CAssay Description:A renin substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair