BDBM149461 US8975252, 4

SMILES COCCCOc1cc(CN(C2CC2)C(=O)[C@H]2CNCCO2)cc2ccccc12

InChI Key InChIKey=PXKWFPHRFQPVMA-JOCHJYFZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 149461   

TargetRenin(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

US Patent
LigandPNGBDBM149461(US8975252, 4)
Affinity DataIC50:  30.2nMT: 2°CAssay Description:A renin substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluoro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRenin(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

US Patent
LigandPNGBDBM149461(US8975252, 4)
Affinity DataIC50:  290nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

US Patent
LigandPNGBDBM149461(US8975252, 4)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed