BDBM150641 US10238633, Example 315::US8987249, 315::US9713606, 315
SMILES Fc1ccc2c(c1)ncc1cc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)ccc21
InChI Key InChIKey=QJNLKABXJHEPTA-IHQHAJGLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 150641
Affinity DataIC50: 13.5nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...More data for this Ligand-Target Pair
Affinity DataIC50: 13.5nMpH: 6.0 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:To activate the proenzyme, 5 μl procathepsin K were mixed with 1 ul activation buffer, and incubated at room temperature for 30 min.5 μL te...More data for this Ligand-Target Pair
Affinity DataIC50: 13.5nMAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 3.5 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F were purchased from PerkinElmer (Prod. No. 6007270). The substrate Z-Gly-Pro-Arg-AMC was from Biomol (Pr...More data for this Ligand-Target Pair