BDBM152619 (E)-2,6-Di-t-butyl-4-((2-(4-(4-Chlorophenyl)thiazole-2-yl)-hydrazono)methyl)-phenol (8)

SMILES CC(C)(C)c1cc(\C=N\Nc2nc(cs2)-c2ccc(Cl)cc2)cc(c1O)C(C)(C)C

InChI Key InChIKey=UNJOWAWAQZCRHW-LGJNPRDNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152619   

TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM152619((E)-2,6-Di-t-butyl-4-((2-(4-(4-Chlorophenyl)thiazo...)
Affinity DataIC50:  1.82E+4nMAssay Description:Inhibition of alpha glucosidase (unknown origin) using p-nitrophenyl glucopyranoside as substrate pre incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Hazara University

LigandPNGBDBM152619((E)-2,6-Di-t-butyl-4-((2-(4-(4-Chlorophenyl)thiazo...)
Affinity DataIC50:  1.82E+4nMpH: 6.8Assay Description:Total volume of 100 µL reaction mixture contained 70 µL 50 mM phosphate buffer pH 6.8, 10 µL test compound (0.5 mM in methanol) followed by the addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed