BDBM152636 (2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]prop-2-en-1-one (M4)

SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F

InChI Key InChIKey=IUJWAWAODSXWTI-DHZHZOJOSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 152636   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Grace College of Pharmacy

LigandPNGBDBM152636((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...)
Affinity DataKi:  360nMpH: 7.4Assay Description:Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Grace College of Pharmacy

LigandPNGBDBM152636((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...)
Affinity DataKi:  900nMpH: 7.4Assay Description:Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Grace College of Pharmacy

LigandPNGBDBM152636((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MAOA using p-tyramine as substrate after 30 mins by Amplex red based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Grace College of Pharmacy

LigandPNGBDBM152636((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human MAOB using benzylamine as substrate after 30 mins by Amplex red based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed