BDBM155105 US9000182, 13, isomer 2

SMILES CC1=N[C@@]2(N=C1N)c1cc(OCCCF)ccc1C[C@@]21CC[C@@H](CC1)OC(F)F

InChI Key InChIKey=WOFHTRRBXQUHFJ-IPHXSNPTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155105   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM155105(US9000182, 13, isomer 2)
Affinity DataIC50:  2.90E+3nMpH: 2.5Assay Description:The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human (3-Secretase (AA 1-AA 460) was clone...More data for this Ligand-Target Pair
In DepthDetails US Patent