BDBM155142 US9000184, 11, isomer 1
SMILES CO[C@H]1CC[C@@]2(CC1)CCc1ccc(cc1C21N=C(C)C(N)=N1)-c1cc(Cl)cc(c1)C#N
InChI Key InChIKey=RDZDAKHZWXGMEB-FIXZJJGLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 155142
Affinity DataIC50: 4.5nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMpH: 2.5Assay Description:TR-FRET Assay: The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human beta -Secretase (AA 1...More data for this Ligand-Target Pair