BDBM15541 4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-5-methyl-1,4-diazepan-2-one::5-methyl diazepanone 13a::5-methyl diazepanone 13b

SMILES CC1CCNC(=O)CN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=WDVOWOZFVGQRFP-HCCKASOXSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 15541   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15541(4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]...)
Affinity DataIC50:  765nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15541(4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]...)
Affinity DataIC50:  1.05E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15541(4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15541(4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15541(4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15541(4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]...)
Affinity DataIC50:  4.40E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed