BDBM15551 (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3,6,6-trimethyl-1,4-diazepan-2-one::6, 6-dimethyl diazepanone 14g

SMILES C[C@H]1N(CC(C)(C)CNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=SAWIDCYIESPFEA-ZYHUDNBSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15551   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15551((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  142nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15551((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  2.60E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15551((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  1.70E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed