BDBM155962 US9018214, 13

SMILES CC(C)c1ccc2CCN(C(=O)CN3CCN[C@H](C)C3)c2c1

InChI Key InChIKey=RTMLXSAEKOYYRI-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 155962   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM155962(US9018214, 13)
Affinity DataIC50:  5.90E+4nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM155962(US9018214, 13)
Affinity DataIC50:  59nMAssay Description:Inhibition of XIAP BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM155962(US9018214, 13)
Affinity DataIC50:  5.90E+4nMAssay Description:Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM155962(US9018214, 13)
Affinity DataIC50:  6.30E+4nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In DepthDetails US Patent