BDBM15870 6-bromo-9-hydroxy-1,3-dimethyl-1H,4H,9H-pyrazolo[3,4-b]quinolin-4-one::9-hydroxy pyrazoloquinolinone 10

SMILES Cc1nn(C)c2n(O)c3ccc(Br)cc3c(=O)c12

InChI Key InChIKey=JNKFWJRBBZEFRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15870   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15870(6-bromo-9-hydroxy-1,3-dimethyl-1H,4H,9H-pyrazolo[3...)
Affinity DataIC50:  920nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed