BDBM15872 6,7-dichloro-9-hydroxy-1-methyl-3-(trifluoromethyl)-1H,4H,9H-pyrazolo[3,4-b]quinolin-4-one::9-hydroxy pyrazoloquinolinone 9b

SMILES Cn1nc(c2c1n(O)c1cc(Cl)c(Cl)cc1c2=O)C(F)(F)F

InChI Key InChIKey=HJIDQTMKQDNUPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15872   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15872(6,7-dichloro-9-hydroxy-1-methyl-3-(trifluoromethyl...)
Affinity DataIC50:  5.14E+3nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed