BDBM15995 2-{[2-(phenylamino)pyrimidin-4-yl]amino}benzamide::4-anilinopyrimidine 2a

SMILES NC(=O)c1ccccc1Nc1ccnc(Nc2ccccc2)n1

InChI Key InChIKey=TVKTVNQGZQPCAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15995   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15995(2-{[2-(phenylamino)pyrimidin-4-yl]amino}benzamide ...)
Affinity DataIC50:  34nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed