BDBM164938 US10166239, Ex. 3-37-6::US11406644, Example 3-37-6::US9067914, Ex. 3-37-6

SMILES COc1ccc(COc2ccc(Cn3c(N)nc4cc(cnc34)-c3cccnc3)cc2OC)cn1

InChI Key InChIKey=BTSSYEBPODNPPC-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 164938   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164938(US10166239, Ex. 3-37-6 | US11406644, Example 3-37-...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164938(US10166239, Ex. 3-37-6 | US11406644, Example 3-37-...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164938(US10166239, Ex. 3-37-6 | US11406644, Example 3-37-...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent