BDBM165925 US10214524, Example 20::US9067931, 20
SMILES OCc1ccc(cc1)-c1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2
InChI Key InChIKey=AWKBLGGBTUCSJU-FQEVSTJZSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 165925
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataKi: 1.60nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataKi: 1.60nM ΔG°: -11.1kcal/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair