BDBM166438 US9073833, 6
SMILES CO\N=C(\C)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1
InChI Key InChIKey=PSORSGLVGFXCQD-STZFKDTASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 166438
Affinity DataIC50: 180nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
Affinity DataIC50: 3.67E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin G using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide as substrate measured for 180 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of Pr3 (unknown origin) using t-butyloxycarbonyl-Ala-Ala-Nva-thiobenzyl ester as substrate measured for 180 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human neutrophil elastase measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair