BDBM17043 Indolinone based inhibitor, 4d::ethyl 2-[(3E)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol-3-ylidene]-2-(1H-pyrrol-2-yl)acetate
SMILES CCOC(=O)C(=C1\C(=O)Nc2ccc(cc12)S(N)(=O)=O)\c1ccc[nH]1
InChI Key InChIKey=FXRJYHONCQIWHF-BUHFOSPRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 17043
Affinity DataIC50: 34nMAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair