BDBM172606 US9090628, 266::US9090628, 287::US9090628, 288

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1ccnn1C1CCCN(C1)C(C)(C)CO

InChI Key InChIKey=XPPGOMOXJOINTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 172606   

LigandPNGBDBM172606(US9090628, 266 | US9090628, 287 | US9090628, 288)
Affinity DataIC50:  0.596nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM172606(US9090628, 266 | US9090628, 287 | US9090628, 288)
Affinity DataIC50:  2.01nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM172606(US9090628, 266 | US9090628, 287 | US9090628, 288)
Affinity DataIC50:  0.292nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent