BDBM173463 US9096601, 8-38
SMILES CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3cccc(NC(=O)C=C)c3)nc12
InChI Key InChIKey=KJFSEEWSSQIOAL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 173463
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 2nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 37nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 0.600nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair