BDBM17431 1,2,4-Triazole Compound, 89::N-(5-{[(3,4-difluorophenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)pyridin-3-amine

SMILES Fc1ccc(CSc2nnc(Nc3cccnc3)[nH]2)cc1F

InChI Key InChIKey=ARJPWOXCGAOYMT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17431   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17431(1,2,4-Triazole Compound, 89 | N-(5-{[(3,4-difluoro...)
Affinity DataKi:  0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed