BDBM174472 US9102670, 4f

SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2ccc(nc2n1)-c1ccc(CNCCO)cc1

InChI Key InChIKey=ZLPWVZYCSHRQHR-OALUTQOASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 174472   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Kudos Pharmaceuticals

US Patent
LigandPNGBDBM174472(US9102670, 4f)
Affinity DataIC50:  1.97nMAssay Description:For mTOR enzyme activity assays, mTOR protein was isolated from HeLa cell cytoplasmic extract by immunoprecipitation, and activity determined essenti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Kudos Pharmaceuticals

US Patent
LigandPNGBDBM174472(US9102670, 4f)
Affinity DataIC50: <2.70nMT: 2°CAssay Description:The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...More data for this Ligand-Target Pair
In DepthDetails US Patent