BDBM176674 US9115122, 76.3

SMILES NCCN1C(=S)S\C(=C/c2ccc3OCOc3c2)C1=O

InChI Key InChIKey=BUBDMZSKWQUTPR-WDZFZDKYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 176674   

TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM176674(US9115122, 76.3)
Affinity DataKd:  1.50E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [T157A](Mus musculus (Mouse))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM176674(US9115122, 76.3)
Affinity DataKd:  8.10E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM176674(US9115122, 76.3)
Affinity DataKd:  4.50E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [T157A,D319N](Mus musculus (mouse))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM176674(US9115122, 76.3)
Affinity DataKd: >2.00E+4nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [D319N](Mus musculus (mouse))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM176674(US9115122, 76.3)
Affinity DataKd:  1.34E+4nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
In DepthDetails US Patent