BDBM178093 [7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine (Compound 5)

SMILES NCC1Cc2cc(F)cc(c2O1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=MWAYPGAGAUFEGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178093   

TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)
Affinity DataIC50:  1.52E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed