BDBM179834 US9676712, 2C

SMILES CC(CCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O

InChI Key InChIKey=CHLXVWPOHSBADP-KMMAFYGUSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179834   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179834(US9676712, 2C)
Affinity DataKi:  2.10nM IC50:  5.70nMpH: 6.0Assay Description:200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3H]PGE2 in the absence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179834(US9676712, 2C)
Affinity DataEC50:  0.00100nMAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179834(US9676712, 2C)
Affinity DataEC50: >1.00E+3nMAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179834(US9676712, 2C)
Affinity DataEC50:  0.00700nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μL of reduced serum medium containing 0.5% FBE. Place ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent