BDBM179839 US9676701, 74 4′-((trans)-2-aminocyclopropyl)-6-methoxybiphenyl-3-carbonitrile hydrochloride
SMILES COc1ccc(cc1-c1ccc(cc1)[C@H]1C[C@@H]1N)C#N
InChI Key InChIKey=OCQWIYBRDBYXAY-ZBFHGGJFSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 179839
Affinity DataKi: 500nM ΔG°: -8.59kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair