BDBM18161 (1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one::(5alpha,17beta)-17-hydroxyandrostan-3-one::CHEMBL27769::DHT::Dihydrotestosterone::[3H]DHT
SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C
InChI Key InChIKey=NVKAWKQGWWIWPM-ABEVXSGRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 18161
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.200nM EC50: 5.10nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -13.8kcal/mole EC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -13.8kcal/mole EC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -13.5kcal/mole EC50: 5.70nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity against Androgen receptor expressed COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity against Human Androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Agonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in cotransfected CV-1 cellMore data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Agonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Agonist activity at human androgen receptor in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair