BDBM182768 US9145414, 24

SMILES N[C@H]1CCCC[C@H]1Nc1nnc(C(N)=O)c(Nc2ccc3cn(nc3c2)C(F)F)n1

InChI Key InChIKey=QHZNYXMPJXZRGL-NWDGAFQWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 182768   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182768(US9145414, 24)
Affinity DataIC50:  0.530nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182768(US9145414, 24)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent publicat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182768(US9145414, 24)
Affinity DataIC50: >1.00E+4nMpH: 7.5Assay Description:Conditions for assaying the in vitro inhibitory activity of the compound against KDR kinase activity were set with reference to the statement in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent