BDBM183676 US9150519, 1-69

SMILES CC(C)CN(C1CCCC1)c1cc(ncn1)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=HDMIXUZKPWZRNL-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183676   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM183676(US9150519, 1-69)
Affinity DataKi:  10nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells were suspended in 50 mM TRI...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM183676(US9150519, 1-69)
Affinity DataEC50:  666nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM183676(US9150519, 1-69)
Affinity DataEC50:  19nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent