BDBM18439 N-(5-methyl-1,2-oxazol-3-yl)-4-[(4-methylbenzene)sulfonamido]benzamide::NCGC00058635::Sulfonamide analogue, 10

SMILES Cc1cc(NC(=O)c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2)no1

InChI Key InChIKey=NPAUELDNSYIBKW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18439   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18439(N-(5-methyl-1,2-oxazol-3-yl)-4-[(4-methylbenzene)s...)
Affinity DataKi:  102nM ΔG°:  -9.40kcal/mole IC50:  168nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed